What We Learned From a 6-Week Evaluation in Aging Dogs
86% showed improved activity or quality of life
Owners are often the first to notice when something starts to change. Maybe their dog isn’t as eager on walks, or doesn’t move through the day with the same energy as before.
These shifts are a natural part of aging, but they raise an important question: what’s actually happening beneath the surface?
Scientists often describe healthy aging using the concept of healthspan, the years a dog remains active, comfortable, and engaged in daily life.
To better understand how supporting cellular energy systems may influence this process, a six-week evaluation was conducted with senior dogs using Amiquip® as part of their daily routine.
In this study, dogs receiving Amiquip® showed measurable changes in metabolic biomarkers associated with cellular energy pathways, along with improvements in owner-reported energy and activity levels.
Quick Study Summary
• Six-week evaluation involving senior dogs
• Daily use of Amiquip® soft chews
• 86% of participating dog owners reported improvements in activity or overall quality-of-life indicators
• Early metabolomic analysis suggested changes in metabolites involved in cellular energy metabolism
• Designed to support cellular systems involved in maintaining healthspan during the natural aging process

Why Cellular Health Matters as Dogs Age
Inside every cell of a dog’s body are structures called mitochondria. These structures convert nutrients into cellular energy that powers movement, muscle activity, and many other biological processes.
As dogs grow older, natural changes occur in cellular metabolism and mitochondrial efficiency. These changes can influence how active and engaged a dog feels in daily life.
Supporting cellular health is one approach that may help maintain healthspan, helping dogs stay active and comfortable during the natural aging process.
Amiquip was formulated with this goal in mind, focusing on nutritional ingredients that support cellular energy systems involved in healthy aging.
Study Overview
A six-week evaluation was conducted to observe how daily use of Amiquip might influence activity and overall quality of life in aging dogs.
Evaluation design
• Duration: 6 weeks
• Participants: senior dogs
• Daily use of Amiquip soft chews
• Owner observations of activity and overall vitality
• Metabolomic analysis examining metabolic pathways involved in cellular energy production
The evaluation explored whether supporting cellular systems involved in energy metabolism could influence everyday activity and engagement.
Key Findings From the Evaluation
At the end of the six-week evaluation, participating dog owners reported noticeable positive changes in many cases.
Owner-reported observations
• 86% of participating dogs showed improvements in activity or overall quality-of-life indicators
• Dogs frequently demonstrated greater engagement in normal daily routines
• Increased enthusiasm for movement and interaction was commonly reported
• Many dogs appeared more interested in walks, play, and household activity
These observations suggest that supporting cellular health may help aging dogs maintain energy and engagement in daily life.

Metabolomic Insights
To better understand what might be driving these changes, we looked at what was happening at the cellular level.
In addition to owner observations, metabolomic analysis was used to examine biochemical markers associated with cellular metabolism.
Metabolomics measures small molecules involved in metabolic pathways and provides insight into how biological systems are functioning at the cellular level.
Early metabolomic signals were consistent with changes in metabolites involved in cellular energy metabolism pathways associated with mitochondrial function.
These pathways help convert nutrients into the cellular energy used by muscles, organs, and tissues throughout the body.
Several metabolites involved in energy metabolism showed patterns consistent with improved metabolic efficiency and energy utilization.
While additional analysis is ongoing, these early findings align with the owner-reported observations of increased activity and engagement during the evaluation period.
What This Means for Aging Dogs
Healthy aging is influenced by many factors, including activity levels, genetics, environment, and nutrition.
Supporting cellular energy systems may play an important role in helping dogs remain active and engaged as they age.
Amiquip was formulated to support these biological systems, helping dog owners take a proactive approach to supporting healthspan during the natural aging process.
Healthy aging is not about slowing down. It’s about supporting the systems that help dogs stay engaged in the life they love.
Types of Supplements That Support Healthy Aging in Dogs
Dog supplements designed for aging support often focus on different biological systems involved in maintaining activity and quality of life.
Common categories include:
Joint structure support
These supplements often include ingredients that help maintain normal joint structure and mobility.
Cognitive support
Some formulas focus on nutrients that support normal brain function and mental engagement in aging dogs.
Cellular health support
A newer category of supplements focuses on cellular metabolism and mitochondrial energy systems that influence how cells produce energy throughout the body.
Amiquip® was developed within this emerging category, focusing on active ingredients that support cellular energy systems involved in healthy aging.
Healthy aging isn’t about slowing down. It’s about supporting the systems that help dogs stay engaged in the life they love.
Frequently Asked Questions
What is healthspan in dogs?
Healthspan refers to the number of years a dog remains active, comfortable, and engaged in everyday life. While lifespan measures how long a dog lives, healthspan focuses on maintaining quality of life throughout those years.
Why do dogs slow down as they age?
As dogs age, natural changes occur in muscle function, metabolism, and cellular energy systems. These changes can influence activity levels and overall vitality.
What is cellular health in dogs?
Cellular health refers to how well a dog’s cells perform their essential functions, including energy production, metabolic activity, and normal biological processes that support daily movement and vitality.
When do dogs begin showing signs of aging?
The aging process varies by breed and size, but many dogs begin entering their senior years between approximately seven and ten years of age.
Research Notes
This evaluation observed changes in activity and owner-reported quality-of-life indicators over a six-week period in senior dogs using Amiquip.
Additional metabolomic analysis is ongoing to further examine metabolic pathways associated with cellular energy production and healthy aging processes.
Supporting Healthspan
Healthy aging is about helping dogs stay active, engaged, and comfortable throughout the years they share with their families.
Amiquip® was developed to support cellular health and energy systems involved in the natural aging process, helping dog owners support their dog’s healthspan for years to come.